Childhood tuberculosis treatment remains imprecise science

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CHILDHOOD RESPIRATORY TUBERCULOSIS IN IRAN

To estimate the bacterio-epidemiological situation of childhood respiratory tuberculosis in Iran, 2185 symptomatic patients of 0-14 years old were studied. Among 110 bacteriologically confirmed cases, 60% were less than five years old and the number of females was slightly more than males. In 21 % of patients, the Mantoux test was negative. None of the miliary cases had a history of BCG va...

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The treatment of tuberculosis in childhood.

992 The treatment of tuberculosis (TB) in children and adults has remained unchanged for more than 30 years, and although new drugs are at last entering clinical trials it will be 5-10 years before their precise place in therapy is established. It is therefore necessary to continue to use our current drugs with care and prudence and be particularly careful about preventing the further developme...

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Treatment of childhood tuberculosis in India.

With a quarter of the global burden of tuberculosis (TB) occurring in India, children in this country are at high risk of tuberculous infection and TB disease. India's Revised National Tuberculosis Control Programme provides free diagnosis and treatment for children with TB using quality assured, weight-based individual drug boxes. Guidelines have recently been revised, updating both the diagno...

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Human bovine tuberculosis - remains in the differential.

Mycobacterium bovis is a pathogen of cattle. The unpasteurized milk of affected cattle is a source of infection in humans. Despite the screening of cattle and the pasteurization of milk, M bovis has not been eradicated. A high index of clinical suspicion is needed in symptomatic patients with a history of possible exposure. At risk groups include animal workers, farmers, meat packers, vets and ...

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Childhood Tuberculosis in Nigeria: Disease Presentation and Treatment Outcomes

Objectives Understanding the factors that influence tuberculosis (TB) treatment outcomes in children is key to designing interventions to address them. This study aimed to determine the case category distribution of childhood TB in Nigeria and assess which clinical and demographic factors are associated with different treatment outcomes in childhood TB. Materials and methods This was a retros...

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ژورنال

عنوان ژورنال: Nature Medicine

سال: 2011

ISSN: 1078-8956,1546-170X

DOI: 10.1038/nm1011-1160a